Friday, April 3, 2026

Recurrence statistics

Is it more likely after "double hit" lymphoma (DBLCL) to get follicular lymphoma or a repeat of DBLCL?

After successful treatment for Diffuse Large B-Cell Lymphoma (DLBCL), it is significantly more likely to have a relapse of the same DLBCL rather than develop follicular lymphoma. While DLBCL can arise from follicular lymphoma (transformation), the reverse is not typical, and relapse usually presents as the same aggressive histology. 

PubMed Central (PMC) (.gov)

Key Findings on DLBCL Recurrence:

Relapse Probability: Approximately 30% to 40% of patients with DLBCL will experience a relapse, generally within the first two years of finishing treatment.


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Wednesday, April 1, 2026

PET scan

 Yet another PET scan! I was hoping to go for two years in between but Dr Ujjani wanted to make sure the shortness of breath I have been experiencing is not due to lymphoma. 

The patient summary says: 

History of follicular lymphoma diagnosed in 2013, treated with rituximab with good response. In 2021, developed high-grade transformation (double-hit lymphoma) with bulky retroperitoneal and nodal disease, treated with R-CHOP followed by dose-adjusted R-EPOCH, achieving complete response.

Now I have to wait for the result on MyChart or the TeleHealth appointment. I'm not worried because I think it's due to weight gain...or a heart problem, more worrisome.  

There is a cardiologist visit in my future!